Who's Who in
Veterinary Medicine Academia

    Jianming Wu

  • Associate Professor
  • Jianming Wu
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  • Department of Veterinary and Biomedical Sciences
  • https://www.vetmed.umn.edu/departments/veterinary-and-biomed...
  • University of Minnesota, Twin Cities
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  • 3 Morrill Hall
    100 Church St. S.E.
    Minneapolis, Minnesota 55455
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  • Contact by e-mail?
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  • I am interested in the functional genomics of human IgG Fc receptors (Fc?Rs) and human inflammatory diseases. Functional genetic variants of Fc?Rs significantly influence the pathogenesis of autoimmune inflammatory diseases such as cancer and autoimmune diseases. We also study genetic mechanisms of human neutrophil antigen (HNA) formation and their role human diseases. Human neutrophil antigen 2 (HNA-2) deficiency is a common phenotype as 3-5% humans do not express HNA-2. HNA-2 deficient individuals are prone to produce HNA-2 alloantibodies that cause a number of disorders including transfusion-related acute lung injury and immune neutropenia.
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