The Galloway-Pena laboratory is dedicated to understanding the molecular basis of pathogenesis and how the microbiota influence the persistence, transmission, and evolution of pathogens. Specifically, the lab’s goal is to understand the microbial factors, resistance determinants, physiological (e.g. gut integrity) and clinical contributors to the development of antibiotic resistance infections in high risk populations, particularly hematologic malignancies. In addition to infectious toxicities, we are also interested in how microbiota and microbial-derived products contribute to cancer progression and cancer therapy response.